Tsuyoshi Nagano: search on Z-Library

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1

AN EPIZOOTIC OF EMERGING NOVEL AVIAN POX IN CARRION CROWS ( CORVUS CORONE ) AND LARGE-BILLED CROWS ( CORVUS MACRORHYNCHOS ) IN JAPAN

Fukui, Daisuke, Nakamura, Makiko, Yamaguchi, Tsuyoshi, Takenaka, Makiko, Murakami, Mami, Yanai, Tokuma, Fukushi, Hideto, Yanagida, Kazumi, Bando, Gen, Matsuno, Keita, Nagano, Masashi, Tsubota, Toshio

Journal:

Journal of Wildlife Diseases

Year:

2016

Language:

english

File:

PDF, 703 KB

english, 2016

2

Optical properties of ultrananocrystalline diamond/amorphous carbon composite films prepared by pulsed laser deposition

Nagano, Akira, Yoshitake, Tsuyoshi, Hara, Takeshi, Nagayama, Kunihito

Journal:

Diamond and Related Materials

Year:

2008

Language:

english

File:

PDF, 409 KB

english, 2008

3

X-ray photoemission spectroscopic study of ultrananocrystalline diamond/hydrogenated amorphous carbon composite films prepared by pulsed laser deposition

Ohmagari, Shinya, Yoshitake, Tsuyoshi, Nagano, Akira, Ohtani, Ryota, Setoyama, Hiroyuki, Kobayashi, Eiichi, Nagayama, Kunihito

Journal:

Diamond and Related Materials

Year:

2010

Language:

english

File:

PDF, 470 KB

english, 2010

4

[IEEE 2014 IEEE Energy Conversion Congress and Exposition (ECCE) - Pittsburgh, PA, USA (2014.9.14-2014.9.18)] 2014 IEEE Energy Conversion Congress and Exposition (ECCE) - Development of flywheel energy storage system with multiple parallel drives

Itoh, Jun-ichi, Nagano, Tsuyoshi, Tanaka, Kenta, Orikawa, Koji, Yamada, Noboru

Year:

2014

Language:

english

File:

PDF, 1.31 MB

english, 2014

5

[IEEE 2014 IEEE 36th International Telecommunications Energy Conference (INTELEC) - Vancouver, BC (2014.9.28-2014.10.2)] 2014 IEEE 36th International Telecommunications Energy Conference (INTELEC) - Development of high efficiency flywheel energ storage system for power load-leveling

Itoh, Jun-ichi, Sato, Daisuke, Nagano, Tsuyoshi, Tanaka, Kenta, Yamada, Noboru, Kato, Koji

Year:

2014

Language:

english

File:

PDF, 1.05 MB

english, 2014

6

[IEEE 2014 IEEE International Power Electronics and Application Conference and Exposition (PEAC) - Shanghai, China (2014.11.5-2014.11.8)] 2014 International Power Electronics and Application Conference and Exposition - A Novel Control Method focusing on reactive power for a dual active bridge converter

Itoh, Jun-ichi, Higa, Hayato, Nagano, Tsuyoshi

Year:

2014

Language:

english

File:

PDF, 885 KB

english, 2014

7

[IEEE IECON 2016 - 42nd Annual Conference of the IEEE Industrial Electronics Society - Florence, Italy (2016.10.23-2016.10.26)] IECON 2016 - 42nd Annual Conference of the IEEE Industrial Electronics Society - Halt sequence for matrix converter to suppress increase of snubber capacitor voltage during motor regeneration

Nagano, Tsuyoshi, Itoh, Jun-ichi

Year:

2016

Language:

english

File:

PDF, 1.33 MB

english, 2016

8

The transport mechanism of metallothionein is different from that of classical NLS-bearing protein

Takayuki Nagano, Norio Itoh, Chikara Ebisutani, Tomoka Takatani, Tomoya Miyoshi, Tsuyoshi Nakanishi, Keiichi Tanaka

Journal:

Journal of Cellular Physiology

Year:

2000

Language:

english

File:

PDF, 200 KB

english, 2000

9

Constitutive expression and delayed light response of casein kinase Iϵ and Iδ mRNAs in the mouse suprachiasmatic nucleus

Yoshiki Ishida, Kazuhiro Yagita, Tsuyoshi Fukuyama, Masataka Nishimura, Mamoru Nagano, Yasufumi Shigeyoshi, Shun Yamaguchi, Takahide Komori, Hitoshi Okamura

Journal:

Journal of Neuroscience Research

Year:

2001

Language:

english

File:

PDF, 177 KB

english, 2001

10

Application of flip-chip bonding method to optical heads

Tsuyoshi Nagano, Ryuichi Katayama, Yuzo Ono

Journal:

Optics & Laser Technology

Year:

1994

Language:

english

File:

PDF, 142 KB

english, 1994

11

Discriminative structural approaches for enzyme active-site prediction

Tsuyoshi Kato, Nozomi Nagano

Journal:

BMC Bioinformatics

Year:

2011

Language:

english

File:

PDF, 444 KB

english, 2011

12

Linkage and haplotype analysis of familial early-onset Alzheimer disease in Japanese population

Kouzin Kamino, Keiko Nagano, Tomohiro Katsuya, Yumiko Nishiwaki, Masatoshi Takeda, Hirotaka Tanabe, Tsuyoshi Nishimura, Kunio Ii, Kenzo Fujimoto, Ryotaro Tsujimura, Yasuhiro Nonomura, Hiroshi Yoneda,

Journal:

Journal of Human Genetics

Year:

1995

Language:

english

File:

PDF, 759 KB

english, 1995

13

The use of axial reconstructed images from three-dimensional MRI datasets for morphological diagnosis of meniscal tears of the knee

Tsuyoshi Ohishi, Masaaki Takahashi, Masashi Abe, Takuya Tsuchikawa, Masashi Mori, Akira Nagano

Journal:

Archives of Orthopaedic and Trauma Surgery

Year:

2005

Language:

english

File:

PDF, 348 KB

english, 2005

14

Clinical significance of bile cytology via an endoscopic nasobiliary drainage tube for pathological diagnosis of malignant biliary strictures

Hiroshi Yagioka, Kenji Hirano, Hiroyuki Isayama, Takeshi Tsujino, Naoki Sasahira, Rie Nagano, Tsuyoshi Hamada, Koji Miyabayashi, Yukiko Ito, Dai Mohri, Kazumichi Kawakubo, Hirofumi Kogure, Takashi Sas

Journal:

Journal of Hepato-Biliary-Pancreatic Sciences

Year:

2011

Language:

english

File:

PDF, 201 KB

english, 2011

15

Gastric acid induces mitochondrial superoxide production and lipid peroxidation in gastric epithelial cells

Hirofumi Matsui, Yumiko Nagano, Osamu Shimokawa, Tsuyoshi Kaneko, Kanho Rai, Jumpei Udo, Aki Hirayama, Yukio Nakamura, Hiroko P. Indo, Hideyuki J. Majima, Ichinosuke Hyodo

Journal:

Journal of Gastroenterology

Year:

2011

Language:

english

File:

PDF, 1.99 MB

english, 2011

16

Questionnaire survey of the current status of radical trachelectomy in Japan

Shinya Sato, Daisuke Aoki, Hiroaki Kobayashi, Tsuyoshi Saito, Ryuichiro Nishimura, Tadayoshi Nagano, Nobuo Yaegashi, Takayuki Enomoto, Junzo Kigawa

Journal:

International Journal of Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 216 KB

english, 2011

17

Neoplastic transformation and induction of H+,K+-adenosine triphosphatase byN-methyl-N′-nitro-N-nitrosoguanidine in the gastric epithelial RGM-1 cell line

Osamu Shimokawa, Hirofumi Matsui, Yumiko Nagano, Tsuyoshi Kaneko, Takeshi Shibahara, Akira Nakahara, Ichinosuke Hyodo, Akinori Yanaka, Hideyuki J. Majima, Yukio Nakamura, Yasushi Matsuzaki

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

2008

Language:

english

File:

PDF, 279 KB

english, 2008

18

Sequential Changes of Bone Metabolism in Normal and Delayed Union of the Spine

Tsuyoshi Ohishi, Masaaki Takahashi, Akihiro Yamanashi, Daisuke Suzuki, Akira Nagano

Journal:

Clinical Orthopaedics and Related Research®

Year:

2008

Language:

english

File:

PDF, 270 KB

english, 2008

19

Detection of Patency of Internal Mammary Artery Grafts to the Left Anterior Descending Artery by Transthoracic Doppler Echocardiography

Hiromi Tasaki, Kazuhito Yamashita, Noriko Hirakawa, Hiroshi Suzuka, Tsuyoshi Morishita, Masahiro Okazaki, Yasuhide Nakashima, Ichiro Nagano

Journal:

Echocardiography

Year:

2006

Language:

english

File:

PDF, 310 KB

english, 2006

20

Mutational screening of APP gene in patients with early-onset Alzheimer disease utilizing mismatched PCR-RFLP

Yumiko Nishiwaki, Kouzin Kamino, Aoi Yoshiiwa, Keiko Nagano, Masatoshi Takeda, Hirotaka Tanabe, Tsuyoshi Nishimura, Toshiko Kobayashi, Hideki Yamamoto, Yasuhiro Nonomura, Hiroshi Yoneda, Toshiaki Saka

Journal:

Clinical Genetics

Year:

1996

Language:

english

File:

PDF, 557 KB

english, 1996

21

ENDOSCOPIC REMOVAL OF A SPONTANEOUSLY FRACTURED BILIARY UNCOVERED SELF-EXPANDABLE METAL STENT

KAZUMICHI KAWAKUBO, HIROYUKI ISAYAMA, TAKESHI TSUJINO, YOUSUKE NAKAI, NAOKI SASAHIRA, HIROFUMI KOGURE, TSUYOSHI HAMADA, RIE NAGANO, KOUJI MIYABAYASHI, KEISUKE YAMAMOTO, DAI MOHRI, TAKASHI SASAKI, YUKI

Journal:

Digestive Endoscopy

Year:

2012

Language:

english

File:

PDF, 718 KB

english, 2012

22

Generation of mouse macrophages expressing membrane-bound TNF variants with selectivity for TNFR1 or TNFR2

Hiroko Shibata, Yasuhiro Abe, Yasuo Yoshioka, Tetsuya Nomura, Masaki Sato, Hiroyuki Kayamuro, Tomoyuki Kawara, Shuhei Arita, Tsuyoshi Furuya, Kazuya Nagano, Tomoaki Yoshikawa, Haruhiko Kamada, Shin-ic

Journal:

Year:

2010

Language:

english

File:

PDF, 472 KB

english, 2010

23

PS3-40 The potential use of IL-1 family cytokines as mucosal adjuvants for a NASA influenza vaccine

Shu-hei Arita, Hiroyuki Kayamuro, Yasuhiro Abe, Yasuo Yoshioka, Haruhiko Kamada, Tsuyoshi Furuya, Norio Itoh, Tomoaki Yoshikawa, Kazuya Nagano, Yasuo Tsutsumi, Shin-ichi Tsunoda

Journal:

Year:

2010

Language:

english

File:

PDF, 61 KB

english, 2010

24

Subunit structure of recombinant rat liver l-tryptophan 2,3-dioxygenase

Surya Prasad Manandhar, Hideo Shimada, Shingo Nagano, Tsuyoshi Egawa, Yuzuru Ishimura

Journal:

International Congress Series

Year:

2002

Language:

english

File:

PDF, 130 KB

english, 2002

25

Arthroscopic resection of an intra-articular osteochondroma of the knee in the patient with multiple osteochondromatosis

Masaaki Takahashi, Atsushi Nishihara, Tsuyoshi Ohishi, Katsumoto Shiga, Kazufumi Yamamoto, Akira Nagano

Journal:

Arthroscopy: The Journal of Arthroscopic & Related Surgery

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

26

Su1442 Dose Extracorporeal Shockwave Lithotripsy Combined With Endotherapy Really Improve the Natural Course of Chronic Pancreatitis?

Naoki Sasahira, Hiroyuki Isayama, Kenji Hirano, Rie Nagano, Tsuyoshi Hamada, Koji Miyabayashi, Keisuke Yamamoto, Dai Mohri, Kazumichi Kawakubo, Hirofumi Kogure, Takashi Sasaki, Yukiko Ito, Yousuke Nak

Journal:

Gastrointestinal Endoscopy

Year:

2011

Language:

english

File:

PDF, 123 KB

english, 2011

27

Su1456 Therapeutic ERCP Using Short Double-Balloon Enteroscopy in Patients With Surgically Altered Anatomy

Hirofumi Kogure, Hirotsugu Watabe, Atsuo Yamada, Hiroyuki Isayama, Takeshi Tsujino, Rie Nagano, Tsuyoshi Hamada, Koji Miyabayashi, Keisuke Yamamoto, Dai Mohri, Kazumichi Kawakubo, Takashi Sasaki, Yuki

Journal:

Gastrointestinal Endoscopy

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

28

Mo1471 Risk Factors for Pancreatitis Following Transpapillary Self-Expandable Metal Stent Placement

Kazumichi Kawakubo, Hiroyuki Isayama, Yousuke Nakai, Naoki Sasahira, Hirofumi Kogure, Tsuyoshi Hamada, Rie Nagano, Koji Miyabayashi, Dai Mohri, Takashi Sasaki, Yukiko Ito, Natsuyo Yamamoto, Kenji Hira

Journal:

Gastrointestinal Endoscopy

Year:

2011

Language:

english

File:

PDF, 187 KB

english, 2011

29

Mo1462 The Effect of Endoscopic Gallbladder Drainage for Management of Acute Cholecystitis

Natsuyo Yamamoto, Hiroyuki Isayama, Kazumichi Kawakubo, Saburo Matsubara, Kenji Hirano, Tsuyoshi Hamada, Rie Nagano, Koji Miyabayashi, Dai Mohri, Hirofumi Kogure, Takashi Sasaki, Naoki Sasahira, Takes

Journal:

Gastrointestinal Endoscopy

Year:

2011

Language:

english

File:

PDF, 64 KB

english, 2011

30

Mo1298 Self-Expandable Metallic Stent With High Axial Force is the Risk Factor of Cholecystitis

Hiroyuki Isayama, Kazumichi Kawakubo, Yousuke Nakai, Hirofumi Kogure, Tsuyoshi Hamada, Osamu Togawa, Rie Nagano, Hiroshi Yagioka, Yukiko Ito, Saburo Matsubara, Takashi Sasaki, Natsuyo Yamamoto, Naoki

Journal:

Gastrointestinal Endoscopy

Year:

2012

Language:

english

File:

PDF, 119 KB

english, 2012

31

Su1384 A Novel Basket Catheter “Reforma” to Facilitate Endoscopic Removal of Pancreatic Stones

Naoki Sasahira, Hiroyuki Isayama, Naminatsu Takahara, Rie Nagano, Tsuyoshi Hamada, Suguru Mizuno, Koji Miyabayashi, Keisuke Yamamoto, Dai Mohri, Kazumichi Kawakubo, Hirofumi Kogure, Takashi Sasaki, Yu

Journal:

Gastrointestinal Endoscopy

Year:

2012

Language:

english

File:

PDF, 321 KB

english, 2012

32

NSAIDs and Acidic Environment Induce Gastric Mucosal Cellular Mitochondrial Dysfunction

Nagano, Yumiko, Matsui, Hirofumi, Tamura, Masato, Shimokawa, Osamu, Nakamura, Yukio, Kaneko, Tsuyoshi, Hyodo, Ichinosuke

Journal:

Year:

2012

Language:

english

File:

PDF, 210 KB

english, 2012

33

Roles of proximal ligand in heme proteins: replacement of proximal histidine of human myoglobin with cysteine and tyrosine by site-directed mutagenesis as models for P-450, chloroperoxidase, and catalase

Adachi, Shinichi, Nagano, Shingo, Ishimori, Koichiro, Watanabe, Yoshihito, Morishima, Isao, Egawa, Tsuyoshi, Kitagawa, Teizo, Makino, Ryu

Journal:

Year:

1993

Language:

english

File:

PDF, 1.98 MB

english, 1993

34

Endoloop ligation technique for prolapsed pedunculated submucous uterine myoma: utility and reliability

Takafumi Ujihira, Tsuyoshi Ota, Hiroshi Nagano…

Journal:

Archives of Gynecology and Obstetrics

Year:

2013

Language:

english

File:

PDF, 312 KB

english, 2013

35

Near-Edge X-Ray Absorption Fine Structure of Ultrananocrystalline Diamond/Hydrogenated Amorphous Carbon Films Prepared by Pulsed Laser Deposition

Ohmagari, Shinya, Yoshitake, Tsuyoshi, Nagano, Akira, AL-Riyami, Sausan, Ohtani, Ryota, Setoyama, Hiroyuki, Kobayashi, Eiichi, Nagayama, Kunihito

Journal:

Journal of Nanomaterials

Year:

2009

Language:

english

File:

PDF, 625 KB

english, 2009

36

Comparison of Biochemical Markers of Bone Turnover and Bone Mineral Density Between Hip Fracture and Vertebral Fracture

Takahashi, Masaaki, Naitou, Kenichi, Ohishi, Tsuyoshi, Nagano, Akira

Journal:

Journal of Clinical Densitometry

Year:

2003

Language:

english

File:

PDF, 227 KB

english, 2003

37

4663436 Leukemia-associated virus immunogen, vaccine and assay

Matsui, Hirofumi, Shimokawa, Osamu, Nagano, Yumiko, Kaneko, Tsuyoshi, Udo, Jumpei, Rai, Kanho, Nakahara, Akira, Hirayama, Aki, Indo, Hiroko, Majima, Hideyuki J., Hyodo, Ichinosuke

Journal:

Biotechnology Advances

Year:

1987

Language:

english

File:

PDF, 65 KB

english, 1987

38

T1084 Gastric Acid Induces Cellular Lipid Peroxidation and Apoptosis by Producing Mitochondrial Superoxide in Gastric Epithelial Cells

Matsui, Hirofumi, Shimokawa, Osamu, Nagano, Yumiko, Kaneko, Tsuyoshi, Udo, Jumpei, Rai, Kanho, Nakahara, Akira, Hirayama, Aki, Indo, Hiroko, Majima, Hideyuki J., Hyodo, Ichinosuke

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 66 KB

english, 2010

39

Ultrasound Measurement Using CUBA Clinical System Can Discriminate Between Women with and without Vertebral Fractures

Ohishi, Tsuyoshi, Kushida, Kazuhiro, Yamazaki, Kaoru, Naitoh, Kenichi, Nagano, Akira

Journal:

Journal of Clinical Densitometry

Year:

2000

Language:

english

File:

PDF, 79 KB

english, 2000

40

Sa1859 An Optical Cancer Diagnosis With Fluorescence Polarization

Kaneko, Tsuyoshi, Matsui, Hirofumi, Shimokawa, Osamu, Nagano, Yumiko, Kanho, Rai, Suzuki, Hideo, Narasaka, Toshiaki, Endo, Shinji, Hisakura, Katsuji, Mizokami, Yuji, Hyodo, Ichinosuke

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 112 KB

english, 2012

41

W1982 Malignant Transformation of Rat Gastric Epithelial RGM-1 Cell Line Induced By Carcinogen N-Methyl-N'-Nitro-N-Nitrosoguanidine (Mnng) Treatment Was Accompanied with the Ectopic Expression of H+,K+-Adenosine Triphosphatase (ATPase)

Shimokawa, Osamu, Matsui, Hirofumi, Kaneko, Tsuyoshi, Nagano, Yumiko, Udo, Jumpei, Mamiya, Takashi, Rai, Kanho, Nakahara, Akira, Hyodo, Ichinosuke

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 68 KB

english, 2008

42

Tu1693 A Prospective Study of a Wallflex Duodenal Stent for Malignant Gastric Outlet Obstruction

Sasaki, Takashi, Isayama, Hiroyuki, Maetani, Iruru, Nakai, Yousuke, Kogure, Hirofumi, Kawakubo, Kazumichi, Nagano, Rie, Hamada, Tsuyoshi, Yagioka, Hiroshi, Ito, Yukiko, Matsubara, Saburo, Yamamoto, Na

Journal:

Gastrointestinal Endoscopy

Year:

2012

Language:

english

File:

PDF, 76 KB

english, 2012

43

W1160 Gastric Cancer Diagnosis With Fluidity Sensitive Fluorescence Measurement

Kaneko, Tsuyoshi, Matsui, Hirofumi, Shimokawa, Osamu, Nagano, Yumiko, Suzuki, Hideo, Fukuda, Kuniaki, Endo, Shinji, Rai, Kanho, Udo, Jumpei, Mamiya, Takashi, Moriwaki, Toshikazu, Abei, Masato, Nakahar

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 50 KB

english, 2010

44

W1060 The Fluorescence Assessment of Cellular Membrane Fluidity in Human Gastric Cancer Specimens

Kaneko, Tsuyoshi, Matsui, Hirofumi, Shimokawa, Osamu, Nakahara, Akira, Shoda, Junichi, Abei, Masato, Fukuda, Kuniaki, Suzuki, Hideo, Moriwaki, Toshikazu, Rai, Kanho, Nagano, Yumiko, Mamiya, Takashi, E

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

45

W1971 Nitric Oxide Mediates the Warburg Effect in Gastric Epithelial and Cancer Cells

Matsui, Hirofumi, Nagano, Yumiko, Shimokawa, Osamu, Kaneko, Tsuyoshi, Udo, Jumpei, Mamiya, Takashi, Rai, Kanho, Hyodo, Ichinosuke, Nakai, Kozi

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 75 KB

english, 2008

46

Role of reactive oxygen species and Ca2+ dissociation from the myofilaments in determination of Ca2+ wave propagation in rat cardiac muscle

Miura, Masahito, Murai, Naomi, Hattori, Taiki, Nagano, Tsuyoshi, Stuyvers, Bruno D., Shindoh, Chiyohiko

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2013

Language:

english

File:

PDF, 988 KB

english, 2013

47

Lower Incidence of Biliary Carcinoma in Patients With Primary Sclerosing Cholangitis and High Serum Levels of Immunoglobulin E

Hirano, Kenji, Tada, Minoru, Mizuno, Suguru, Isayama, Hiroyuki, Takahara, Naminatsu, Nagano, Rie, Hamada, Tsuyoshi, Miyabayashi, Koji, Ito, Yukiko, Mohri, Dai

Journal:

Clinical Gastroenterology and Hepatology

Year:

2012

Language:

english

File:

PDF, 477 KB

english, 2012

48

[IEEE 2013 15th European Conference on Power Electronics and Applications (EPE) - Lille, France (2013.09.2-2013.09.6)] 2013 15th European Conference on Power Electronics and Applications (EPE) - Verification of parallel connected multiple motor drive system with numbers of permanent magnet synchronous motors

Nagano, Tsuyoshi, Chiang, Goh Teck, Itoh, Jun-ichi, Kato, Koji

Year:

2013

Language:

english

File:

PDF, 417 KB

english, 2013

49

Infrared Spectroscopic and Mutational Studies on Putidaredoxin-Induced Conformational Changes in Ferrous CO-P450cam †,‡

Nagano, Shingo, Shimada, Hideo, Tarumi, Akiko, Hishiki, Takako, Kimata-Ariga, Yoko, Egawa, Tsuyoshi, Suematsu, Makoto, Park, Sam-Yong, Adachi, Shin-ichi, Shiro, Yoshitsugu, Ishimura, Yuzuru

Journal:

Year:

2003

Language:

english

File:

PDF, 194 KB

english, 2003

50

Ultrananocrystalline Diamond/Hydrogenated Amorphous Carbon Films Prepared by a Coaxial Arc Plasma Gun

Nakagawa, You, Yoshitake, Tsuyoshi, Hanada, Kenji, Nagano, Akira, Ohtani, Ryota, Sumitani, Kazushi, Setoyama, Hiroyuki, Kobayashi, Eiichi, Hirakawa, Masaaki, Yamaguchi, Koichi, Tsukahara, Naoki, Agawa

Journal:

Materials Science Forum

Year:

2010

Language:

english

File:

PDF, 475 KB

english, 2010